Thymosin-β4 10mg (Without Mannitol)

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.


Thymosin-β4 Peptide Sequence
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-lle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular formula: C212H350N56O78S
Molar Mass: 4963.4408
CAS number: 77591-33-4
PubChem: CID 16132341

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What Is TB-500?

TB-500, a synthetic analogue comprising 43 amino acids, mimics thymosin beta-4 (TB-4), a naturally occurring component present in almost all mammalian cells. Recognized for its influence on actin protein, cell migration, and wound healing, TB-500 has demonstrated its efficacy in animal models and in vitro analyses by enhancing blood vessel growth, expediting wound healing, mitigating inflammation, and fostering the production of extracellular matrix. Presently, research is actively exploring its potential to mitigate oxidative stress in spinal cord injuries, aid recovery post-heart attacks, and unveil its manifold anti-aging properties.

TB-500 Mechanism of Action
TB-500, derived from TB-4, functions as the active domain predominantly acting as an actin binding protein. Actin, a pivotal element in cell structure, constitutes microfilaments, essential in various cellular functions. Microfilaments play key roles in maintaining cell shape, safeguarding cell membrane integrity, facilitating cell movement, and participating in specific stages of cellular reproduction. Actin also stands as a primary component within muscle protein, crucial for muscle contraction. Actin binding proteins, such as TB-4, safeguard actin monomers, the fundamental building blocks of actin, preserving them from degradation and ensuring their availability for polymerization into microfilaments as needed.