IGF-1 LR3 (1mg)

$150.00

Reconstitution Warranty Notice (Research Use Only)

For laboratory research use only. Not for human use.
Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in
accordance with generally accepted research practices.
Warranty related to reconstitution, sterility, or material integrity applies only when Canlab
Bacteriostatic Water is used. Use of third-party diluents or deviation from provided handling
guidance voids any applicable warranty.
For full handling instructions and limitations, please refer to the Peptide Reconstitution,
Research Use Only section in our 

  Product Warranty Policy Page.

IGF1-LR3 Structure
Sequence: MFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK
PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA
Molecular Formula: C400H625N1110115S9
Molecular Weight: 9117.5 g/mol
CAS Number: 946870-92-4

Description

IGF1-LR3 stands as a modified variant of insulin-like growth factor-1, known by its complete designation as insulin-like growth factor-1 long arginine 3. All derivatives of IGF-1 significantly contribute to cellular division, proliferation, and intercellular communication. Despite sharing similar effects, IGF-1 LR3 exhibits a weaker binding affinity to IGF binding proteins in comparison to IGF-1. Consequently, IGF1-LR3 remains in circulation around 120 times longer than IGF-1. This prolonged half-life of IGF1-LR3 stems from structural modifications; the peptide’s formulation involves the addition of 13 amino acids to the N-terminal end of IGF-1 and the transformation of glutamic acid at position 3 of IGF-1 into an arginine residue.

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