TP508 (5mg)

TP508, also known as Chrysalin or rusalatide acetate. Here’s an overview of TP508:

Overview: TP508 is a synthetic 23-amino-acid peptide derived from a region of human thrombin. This peptide plays a crucial role in initiating tissue revascularization, regeneration, and repair at injury sites. It has been developed to address various medical conditions by promoting healing and reducing inflammation.

Mechanism of Action: TP508 binds to specific receptors on endothelial cells, stem cells, and certain inflammatory cells. Upon binding, it activates signaling pathways that:

• Restore Vascular Function: Enhances blood flow and reduces vascular damage.
• Stimulate Stem Cell Activity: Promotes proliferation and mobilization of progenitor stem cells.

Reduce Inflammation: Modulates inflammatory responses to aid in tissue repair.

Clinical Applications: Preclinical and clinical studies have explored TP508’s potential in:

• • Dermal Wound Healing: Accelerating the repair of skin injuries, including diabetic foot ulcers.
  • Fracture Repair: Enhancing bone healing processes.
  • Radiation Damage Mitigation: Reducing tissue damage from radiation exposure.
  • Acute Respiratory Distress Syndrome (ARDS): Addressing vascular damage and inflammation associated with ARDS.