TP508 – 5mg

$80.00

587 in stock

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.


Molecular Weight:
2312.44
Formula: C97H146N28O36S
CAS No.: 121341-81-9
Sequence: Ala-Gly-Tyr-Lys-Pro-Asp-Glu-Gly-Lys-Arg-Gly-Asp-Ala-Cys-Glu-Gly-Asp-Ser-Gly-Gly-Pro-Phe-Val
Sequence Shortening: AGYKPDEGKRGDACEGDSGGPFV

Description

TP508, also known as Chrysalin or rusalatide acetate. Here’s an overview of TP508:

Overview: TP508 is a synthetic 23-amino-acid peptide derived from a region of human thrombin. This peptide plays a crucial role in initiating tissue revascularization, regeneration, and repair at injury sites. It has been developed to address various medical conditions by promoting healing and reducing inflammation.

Mechanism of Action: TP508 binds to specific receptors on endothelial cells, stem cells, and certain inflammatory cells. Upon binding, it activates signaling pathways that:

  • Restore Vascular Function: Enhances blood flow and reduces vascular damage.
  • Stimulate Stem Cell Activity: Promotes proliferation and mobilization of progenitor stem cells.

Reduce Inflammation: Modulates inflammatory responses to aid in tissue repair.

Clinical Applications: Preclinical and clinical studies have explored TP508’s potential in:

    • Dermal Wound Healing: Accelerating the repair of skin injuries, including diabetic foot ulcers.
    • Fracture Repair: Enhancing bone healing processes.
    • Radiation Damage Mitigation: Reducing tissue damage from radiation exposure.
    • Acute Respiratory Distress Syndrome (ARDS): Addressing vascular damage and inflammation associated with ARDS.

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