Vesilute, among dipeptides, exhibits a widespread presence in various bodily tissues, representing one of the less explored Khavinson peptides[1]. While it remains relatively understudied, Vesilute shows potential effects on bladder and genitourinary tissues. Reports from research suggest its ability to enhance bladder function, particularly in aging individuals, aiding in chronic cystitis, benign prostatic hyperplasia (BPH), and assorted urinary concerns. Its significant organotropic impact extends to the prostate, where it contributes to curbing cell proliferation and mitigating prostate enlargement, potentially attributed to enhanced microcirculation.
Studies propose that Vesilute and other cytomedines positively influence sperm quality and fertility. Russian research has highlighted their role in boosting sperm production, improving health and viability, while reducing abnormalities, thus promoting fertility[2]. Intriguingly, the Glu-Asp peptide, along with a dozen other dipeptides, has been linked to the umami flavor across various contexts[3]. While not directly associated with health, the pleasurable taste possibly suggests an evolutionary preference for their ingestion. This hints at a potential role in fundamental biochemical processes, although this remains speculative. Notably, Vesilute and other cytomedines have exhibited oral bioactivity[2].