FOX-04 (2mg)
North American Research Supply

FOX-04 (2mg)

$200.00

✓Quality documentation available
Reconstitution Warranty Notice (Research Use Only)

For laboratory research use only. Not for human use.

  • Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
  • Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in accordance with generally accepted research practices.
  • Warranty related to reconstitution, sterility or material integrity applies only when Canlab Bacteriostatic Water is used.
  • Use of third-party diluents or deviation from the provided handling guidance voids any applicable warranty.

For full handling instructions and limitations, see the Peptide Reconstitution, Research Use Only section in our Product Warranty Policy Page →

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Description

FOXO4-DRI (Retro-Inverso) is a synthetic, modified variant of the FOXO4 protein designed to extend its stability and alter its biological activity. This modification enables it to disrupt the normal interaction between FOXO4 and p53, a regulatory protein involved in the survival of senescent cells. By preventing FOXO4 from binding to p53, FOXO4-DRI allows damaged senescent cells to undergo apoptosis, thereby facilitating their removal. Clearing these senescent cells has been associated in research settings with improved tissue function, reduced inflammation, and better overall organ health. Animal studies suggest that FOXO4-DRI may contribute to cellular rejuvenation and improvements in various markers related to aging. Its activity also appears to intersect with pathways involved in oxidative stress, insulin sensitivity, and cell cycle control, positioning it as a compound of interest in senolytic and regenerative medicine research.

Additional Information
SKUCL-FOX04-2MG
CategoryPeptides
Benefits

Please review the complete product description and available supporting documentation for product-specific research information. This product is sold strictly for laboratory research use.

Mechanism of Action

Refer to the product description, certificate of analysis and applicable published research for product-specific information. No medical or therapeutic claims are made.

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