Selank, originating from Russia, stands as a brief peptide possessing both nootropic and anxiolytic attributes. Serving as a synthetic counterpart to the naturally existing Tuftsin, an immunomodulatory peptide, Selank mirrors Tuftsin closely, differing mainly by containing an additional four amino acids in its chain. This modification aids in enhancing its metabolic stability and extending its half-life.
Notably, Selank, like Tuftsin, influences IL-6, T helper cells, monoamine neurotransmitters, and brain-derived neurotrophic factor (BDNF). The fundamental similarities between Selank and Tuftsin lie in their structure, with Selank’s slight alteration in amino acids contributing to improved stability and longevity.
Clinical trials have explored Selank’s potential application as a treatment for generalized anxiety disorder.