ARA-290 (12mg)
$77.00
- Sequence
- ZEQLERALNSS
- Molecular Formula
- C51H84N16021
- Molecular Weight
- 1257.3 g/mol
- PubChem CID
- 91810664
- CAS Number
- 1208243-50-8
- Synonyms
- cibinetide, PH-BSP
For laboratory research use only. Not for human use.
- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in accordance with generally accepted research practices.
- Warranty related to reconstitution, sterility or material integrity applies only when Canlab Bacteriostatic Water is used.
- Use of third-party diluents or deviation from the provided handling guidance voids any applicable warranty.
For full handling instructions and limitations, see the Peptide Reconstitution, Research Use Only section in our Product Warranty Policy Page →
Description
ARA-290, a small peptide derived from the helix beta domain of erythropoietin (EPO), possesses diverse therapeutic properties separate from its conventional role in stimulating red blood cell production in the bone marrow. EPO, a glycoprotein primarily synthesized in the kidney, demonstrates a range of actions including fostering blood vessel growth, supporting cell survival, influencing blood pressure, and providing neuroprotective effects in diabetic neuropathy. ARA-290 specifically delivers the neuroprotective and pain-relieving benefits associated with EPO while abstaining from the stimulation of red blood cell production[1].
Having successfully concluded phase II trials, ARA-290 is poised to progress into phase III trials, targeting various applications in diabetes and autoimmune sarcoidosis. Presently, the peptide garners significant attention for its efficacy in managing neuropathic pain. Additionally, ongoing research explores its potential as a catalyst for wound repair in chronic diabetes, an immune-modulating agent, and a plausible treatment option for systemic lupus erythematosus (lupus or SLE).
Additional Information
Benefits
Please review the complete product description and available supporting documentation for product-specific research information. This product is sold strictly for laboratory research use.
Mechanism of Action
Refer to the product description, certificate of analysis and applicable published research for product-specific information. No medical or therapeutic claims are made.
