Colivelin (0.5mg)

$50.00

Reconstitution Warranty Notice (Research Use Only)

For laboratory research use only. Not for human use.
Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in
accordance with generally accepted research practices.
Warranty related to reconstitution, sterility, or material integrity applies only when Canlab
Bacteriostatic Water is used. Use of third-party diluents or deviation from provided handling
guidance voids any applicable warranty.
For full handling instructions and limitations, please refer to the Peptide Reconstitution,
Research Use Only section in our 

  Product Warranty Policy Page.

Sequence one letter code: SALLRSIPAPAGASRLLLLTGEIDLP
Sequence three letter code: H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH
CAS registry number: 867021-83-8
Molecular Formula: C119H206N32O35
Molecular Mass/ Weight: 2645.3

Description

This novel peptide, colivelin, was engineered to enhance the neuroprotective capabilities of humanin (HN). It combines Activity-Dependent Neurotrophic Factor (ADNF) with AGA-(C8R) HNG17, a robust HN derivative. Colivelin has demonstrated remarkable potential by entirely halting cell death triggered by overexpressed genes causing Familial Alzheimer’s disease (FAD) and beta-amyloid (1-43). When administered intraperitoneally, colivelin effectively mitigates memory impairment, presenting itself as a promising candidate for the treatment of Alzheimer’s disease.

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