North American Research Supply

Thymosin-β4 (10mg)

$130.00

Quality documentation available
Product SpecificationsReference data - research use only
Sequence
Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-lle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser
Molecular Formula
C212H350N56O78S
Molecular Weight
4963.4408
PubChem CID
CID 16132341
CAS Number
77591-33-4
Reconstitution Warranty Notice (Research Use Only)

For laboratory research use only. Not for human use.

  • Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
  • Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in accordance with generally accepted research practices.
  • Warranty related to reconstitution, sterility or material integrity applies only when Canlab Bacteriostatic Water is used.
  • Use of third-party diluents or deviation from the provided handling guidance voids any applicable warranty.

For full handling instructions and limitations, see the Peptide Reconstitution, Research Use Only section in our Product Warranty Policy Page →

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Description

What Is TB-500?

TB-500, a synthetic analogue comprising 43 amino acids, mimics thymosin beta-4 (TB-4), a naturally occurring component present in almost all mammalian cells. Recognized for its influence on actin protein, cell migration, and wound healing, TB-500 has demonstrated its efficacy in animal models and in vitro analyses by enhancing blood vessel growth, expediting wound healing, mitigating inflammation, and fostering the production of extracellular matrix. Presently, research is actively exploring its potential to mitigate oxidative stress in spinal cord injuries, aid recovery post-heart attacks, and unveil its manifold anti-aging properties.

TB-500 Mechanism of Action
TB-500, derived from TB-4, functions as the active domain predominantly acting as an actin binding protein. Actin, a pivotal element in cell structure, constitutes microfilaments, essential in various cellular functions. Microfilaments play key roles in maintaining cell shape, safeguarding cell membrane integrity, facilitating cell movement, and participating in specific stages of cellular reproduction. Actin also stands as a primary component within muscle protein, crucial for muscle contraction. Actin binding proteins, such as TB-4, safeguard actin monomers, the fundamental building blocks of actin, preserving them from degradation and ensuring their availability for polymerization into microfilaments as needed.

Additional Information
SKUCL-THYMOSINB4-10MG
CategoryPeptides
Benefits

Please review the complete product description and available supporting documentation for product-specific research information. This product is sold strictly for laboratory research use.

Mechanism of Action

Refer to the product description, certificate of analysis and applicable published research for product-specific information. No medical or therapeutic claims are made.

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