Colivelin (0.5mg)
$70.00
- Sequence (single letter)
- SALLRSIPAPAGASRLLLLTGEIDLP
- Sequence (three letter)
- H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH
- Molecular Formula
- C119H206N32O35
- Molecular Weight
- 2645.3
- CAS Number
- 867021-83-8
For laboratory research use only. Not for human use.
- Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
- Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in accordance with generally accepted research practices.
- Warranty related to reconstitution, sterility or material integrity applies only when Canlab Bacteriostatic Water is used.
- Use of third-party diluents or deviation from the provided handling guidance voids any applicable warranty.
For full handling instructions and limitations, see the Peptide Reconstitution, Research Use Only section in our Product Warranty Policy Page →
Description
This novel peptide, colivelin, was engineered to enhance the neuroprotective capabilities of humanin (HN). It combines Activity-Dependent Neurotrophic Factor (ADNF) with AGA-(C8R) HNG17, a robust HN derivative. Colivelin has demonstrated remarkable potential by entirely halting cell death triggered by overexpressed genes causing Familial Alzheimer’s disease (FAD) and beta-amyloid (1-43). When administered intraperitoneally, colivelin effectively mitigates memory impairment, presenting itself as a promising candidate for the treatment of Alzheimer’s disease.
Additional Information
Benefits
Please review the complete product description and available supporting documentation for product-specific research information. This product is sold strictly for laboratory research use.
Mechanism of Action
Refer to the product description, certificate of analysis and applicable published research for product-specific information. No medical or therapeutic claims are made.
