Colivelin 0.5 mg

Product Usage: This PRODUCT IS INTENDED AS A RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused or mislabeled as a drug, food, or cosmetic.

Sequence one letter code:
Sequence three letter code: H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH
CAS registry number: 867021-83-8
Molecular Formula: C119H206N32O35
Molecular Mass/ Weight: 2645.3

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This novel peptide, colivelin, was engineered to enhance the neuroprotective capabilities of humanin (HN). It combines Activity-Dependent Neurotrophic Factor (ADNF) with AGA-(C8R) HNG17, a robust HN derivative. Colivelin has demonstrated remarkable potential by entirely halting cell death triggered by overexpressed genes causing Familial Alzheimer’s disease (FAD) and beta-amyloid (1-43). When administered intraperitoneally, colivelin effectively mitigates memory impairment, presenting itself as a promising candidate for the treatment of Alzheimer’s disease.