North American Research Supply

CJC 1295 – No DAC (mod GRF 1-29) (5mg)

$55.00

Quality documentation available

In stock

Product SpecificationsReference data - research use only
Sequence
Tyr-D-Ala-Asp-Ala-lle-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-lle-Leu-Ser-Arg
Molecular Formula
C152H252N44042
Molecular Weight
3367.954 g/mol
PubChem CID
56841945
CAS Number
863288-34-0
Reconstitution Warranty Notice (Research Use Only)

For laboratory research use only. Not for human use.

  • Lyophilized peptides should be reconstituted using proper aseptic laboratory technique.
  • Reconstitution must be performed using Canlab-supplied Bacteriostatic Water and handled in accordance with generally accepted research practices.
  • Warranty related to reconstitution, sterility or material integrity applies only when Canlab Bacteriostatic Water is used.
  • Use of third-party diluents or deviation from the provided handling guidance voids any applicable warranty.

For full handling instructions and limitations, see the Peptide Reconstitution, Research Use Only section in our Product Warranty Policy Page →

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Description

Modified GRF (1-29) serves as a peptide analogue derived from growth-hormone-releasing hormone (GHRH). Its development in the 1980s stemmed from the revelation that the initial 29 amino acids of GHRH preserved all characteristics of the complete 44-amino-acid protein. The original protein, GRF (1-29), represents the smallest fragment of GHRH maintaining its entire functionality. Another abbreviated synthetic variation, known as Sermorelin or GRF 1-29, comprises 29 amino acids, whereas Modified GRF (1-29) undergoes further modifications by substituting four amino acids within its chain. These substitutions are aimed at preventing degradation and oxidation during manufacturing, transportation, and within the body, concurrently enhancing its affinity to bind with GHRH receptors.

While GRF exhibited full efficacy, its short half-life (less than 10 minutes) limited its duration of action. Consequently, researchers modified GRF (1-29) to extend its half-life, thus amplifying its therapeutic potential. Occasional references to Modified GRF (1-29) include terms like mod GRF or tetrasubstituted GRF (1-29), emphasizing the distinction from GRF (1-29) due to the alteration of four amino acids. Notably, Modified GRF (1-29) mirrors CJC-1295 without DAC in its composition.

Additional Information
SKUCL-CJC1295NODAC-5MG
CategoryPeptides
Benefits

Please review the complete product description and available supporting documentation for product-specific research information. This product is sold strictly for laboratory research use.

Mechanism of Action

Refer to the product description, certificate of analysis and applicable published research for product-specific information. No medical or therapeutic claims are made.

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